GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells

GM-CSF (Csf-2) is a critical cytokine for the in vitro generation of dendritic cells (DCs) and is thought to control the development of inflammatory DCs and resident CD103(+) DCs in some tissues. Here we showed that in contrast to the current understanding, Csf-2 receptor acts in the steady state to...

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Hoofdauteurs: Greter, Melanie, Helft, Julie, Chow, Andrew, Hashimoto, Daigo, Mortha, Arthur, Agudo-Cantero, Judith, Bogunovic, Milena, Gautier, Emmanuel L., Miller, Jennifer, Leboeuf, Marylene, Lu, Geming, Aloman, Costica, Brown, Brian D., Pollard, Jeffrey W., Xiong, Huabao, Randolph, Gwendalyn J., Chipuk, Jerry E., Frenette, Paul S., Merad, Miriam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498051/
https://ncbi.nlm.nih.gov/pubmed/22749353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.027
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