AMPK β1 reduces tumor progression and improves survival in p53 null mice

The AMP‐activated protein kinase (AMPK) is a heterotrimeric protein complex that is an important sensor of cellular energy status. Reduced expression of the AMPK β1 isoform has been linked to reduced survival in different cancers, but whether this accelerates tumor progression and the potential mech...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Houde, Vanessa P., Donzelli, Sara, Sacconi, Andrea, Galic, Sandra, Hammill, Joanne A., Bramson, Jonathan L., Foster, Robert A., Tsakiridis, Theodoros, Kemp, Bruce E., Grasso, Giuseppe, Blandino, Giovanni, Muti, Paola, Steinberg, Gregory R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579332/
https://ncbi.nlm.nih.gov/pubmed/28544264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12079
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