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Oncogenomic Approaches in Exploring Gain of Function of Mutant p53
Cancer is caused by the spatial and temporal accumulation of alterations in the genome of a given cell. This leads to the deregulation of key signalling pathways that play a pivotal role in the control of cell proliferation and cell fate. The p53 tumor suppressor gene is the most frequent target in...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Bentham Science Publishers Ltd.
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679646/ https://ncbi.nlm.nih.gov/pubmed/19440517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920208784340713 |
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