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Oncogenomic Approaches in Exploring Gain of Function of Mutant p53

Cancer is caused by the spatial and temporal accumulation of alterations in the genome of a given cell. This leads to the deregulation of key signalling pathways that play a pivotal role in the control of cell proliferation and cell fate. The p53 tumor suppressor gene is the most frequent target in...

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Detalhes bibliográficos
Main Authors: Donzelli, Sara, Biagioni, Francesca, Fausti, Francesca, Strano, Sabrina, Fontemaggi, Giulia, Blandino, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679646/
https://ncbi.nlm.nih.gov/pubmed/19440517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920208784340713
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