AMPK β1 reduces tumor progression and improves survival in p53 null mice

The AMP‐activated protein kinase (AMPK) is a heterotrimeric protein complex that is an important sensor of cellular energy status. Reduced expression of the AMPK β1 isoform has been linked to reduced survival in different cancers, but whether this accelerates tumor progression and the potential mech...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Houde, Vanessa P., Donzelli, Sara, Sacconi, Andrea, Galic, Sandra, Hammill, Joanne A., Bramson, Jonathan L., Foster, Robert A., Tsakiridis, Theodoros, Kemp, Bruce E., Grasso, Giuseppe, Blandino, Giovanni, Muti, Paola, Steinberg, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579332/
https://ncbi.nlm.nih.gov/pubmed/28544264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12079
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