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Tumour heterogeneity promotes collective invasion and cancer metastatic dissemination

Heterogeneity within tumour cell populations is commonly observed in most cancers. However, its impact on metastatic dissemination, one of the primary determinants of the disease prognosis, remains poorly understood. Working with a simplified numerical model of tumour spheroids, we investigated the...

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Detalhes bibliográficos
Publicado no:R Soc Open Sci
Main Authors: Hallou, Adrien, Jennings, Joel, Kabla, Alexandre J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579073/
https://ncbi.nlm.nih.gov/pubmed/28878958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.161007
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