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Tumour heterogeneity promotes collective invasion and cancer metastatic dissemination

Heterogeneity within tumour cell populations is commonly observed in most cancers. However, its impact on metastatic dissemination, one of the primary determinants of the disease prognosis, remains poorly understood. Working with a simplified numerical model of tumour spheroids, we investigated the...

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Detalles Bibliográficos
Publicado en:R Soc Open Sci
Main Authors: Hallou, Adrien, Jennings, Joel, Kabla, Alexandre J.
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society Publishing 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579073/
https://ncbi.nlm.nih.gov/pubmed/28878958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.161007
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