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Tumour heterogeneity promotes collective invasion and cancer metastatic dissemination

Heterogeneity within tumour cell populations is commonly observed in most cancers. However, its impact on metastatic dissemination, one of the primary determinants of the disease prognosis, remains poorly understood. Working with a simplified numerical model of tumour spheroids, we investigated the...

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Podrobná bibliografie
Vydáno v:R Soc Open Sci
Hlavní autoři: Hallou, Adrien, Jennings, Joel, Kabla, Alexandre J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society Publishing 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579073/
https://ncbi.nlm.nih.gov/pubmed/28878958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.161007
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