A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumor progression

The contribution of lncRNAs to tumor progression and regulatory mechanisms driving their expression are areas of intense investigation. Here, we characterize the binding of heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1) to a nucleic acid structural element located in exon 12 of PNUTS (also kn...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Grelet, Simon, Link, Laura A., Howley, Breege, Obellianne, Clémence, Palanisamy, Viswanathan, Gangaraju, Vamsi K., Diehl, J. Alan, Howe, Philip H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578890/
https://ncbi.nlm.nih.gov/pubmed/28825698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3595
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