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Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia

Colorectal cancer (CRC) is characterized by genome-wide alterations to DNA methylation that influence gene expression and genomic stability. Less is known about the extent to which methylation is disrupted in the earliest stages of CRC development. In this study we have combined laser-capture microd...

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Podrobná bibliografie
Vydáno v:Oncogene
Hlavní autoři: Hanley, Matthew P., Hahn, Maria A., Li, Arthur X., Wu, Xiwei, Lin, Jianan, Wang, Jinhui, Choi, Audrey, Ouyang, Zhengqing, Fong, Yuman, Pfeifer, Gerd P., Devers, Thomas J., Rosenberg, Daniel W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578878/
https://ncbi.nlm.nih.gov/pubmed/28459462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.130
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