Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia

Colorectal cancer (CRC) is characterized by genome-wide alterations to DNA methylation that influence gene expression and genomic stability. Less is known about the extent to which methylation is disrupted in the earliest stages of CRC development. In this study we have combined laser-capture microd...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Hanley, Matthew P., Hahn, Maria A., Li, Arthur X., Wu, Xiwei, Lin, Jianan, Wang, Jinhui, Choi, Audrey, Ouyang, Zhengqing, Fong, Yuman, Pfeifer, Gerd P., Devers, Thomas J., Rosenberg, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578878/
https://ncbi.nlm.nih.gov/pubmed/28459462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.130
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