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Hippocampal Perineuronal Nets Are Required for the Sustained Antidepressant Effect of Ketamine
BACKGROUND: N-methyl-D-aspartate receptor antagonists, like ketamine, produce a rapid-acting and long-lasting antidepressant effect. Although the mechanism is not completely understood, ketamine is thought to preferentially target N-methyl-D-aspartate receptors on fast-spiking parvalbumin-containing...
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| Published in: | Int J Neuropsychopharmacol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578802/ https://ncbi.nlm.nih.gov/pubmed/27806991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyw095 |
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