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The role of the C-terminal D0 domain of flagellin in activation of Toll like receptor 5
Flagellin is a wide-spread bacterial virulence factor sensed by the membrane-bound Toll-like receptor 5 (TLR5) and by the intracellular NAIP5/NLRC4 inflammasome receptor. TLR5 recognizes a conserved region within the D1 domain of flagellin, crucial for the interaction between subunits in the flagell...
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| Pubblicato in: | PLoS Pathog |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578693/ https://ncbi.nlm.nih.gov/pubmed/28827825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006574 |
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