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Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb

Epigenomic mapping of enhancer-associated chromatin modifications facilitates the genome-wide discovery of tissue-specific enhancers in vivo. However, reliance on single chromatin marks leads to high rates of false-positive predictions. More sophisticated, integrative methods have been described, bu...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Monti, Remo, Barozzi, Iros, Osterwalder, Marco, Lee, Elizabeth, Kato, Momoe, Garvin, Tyler H., Plajzer-Frick, Ingrid, Pickle, Catherine S., Akiyama, Jennifer A., Afzal, Veena, Beerenwinkel, Niko, Dickel, Diane E., Visel, Axel, Pennacchio, Len A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578682/
https://ncbi.nlm.nih.gov/pubmed/28827824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005720
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