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Peptide B targets soluble guanylyl cyclase α1 and kills prostate cancer cells

Among androgen-regulated genes, soluble guanylyl cyclase α1 (sGCα1) is significant in promoting the survival and growth of prostate cancer cells and does so independent of nitric oxide (NO) signaling. Peptides were designed targeting sGCα1 to block its pro-cancer functions and one peptide is discuss...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Zhou, Jun, Gao, Shuai, Hsieh, Chen-Lin, Malla, Mamata, Shemshedini, Lirim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578680/
https://ncbi.nlm.nih.gov/pubmed/28859127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184088
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