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Peptide B targets soluble guanylyl cyclase α1 and kills prostate cancer cells

Among androgen-regulated genes, soluble guanylyl cyclase α1 (sGCα1) is significant in promoting the survival and growth of prostate cancer cells and does so independent of nitric oxide (NO) signaling. Peptides were designed targeting sGCα1 to block its pro-cancer functions and one peptide is discuss...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Zhou, Jun, Gao, Shuai, Hsieh, Chen-Lin, Malla, Mamata, Shemshedini, Lirim
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578680/
https://ncbi.nlm.nih.gov/pubmed/28859127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184088
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