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Peptide B targets soluble guanylyl cyclase α1 and kills prostate cancer cells

Among androgen-regulated genes, soluble guanylyl cyclase α1 (sGCα1) is significant in promoting the survival and growth of prostate cancer cells and does so independent of nitric oxide (NO) signaling. Peptides were designed targeting sGCα1 to block its pro-cancer functions and one peptide is discuss...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Zhou, Jun, Gao, Shuai, Hsieh, Chen-Lin, Malla, Mamata, Shemshedini, Lirim
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578680/
https://ncbi.nlm.nih.gov/pubmed/28859127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184088
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