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Soluble Guanylyl Cyclase α1 and p53 Cytoplasmic Sequestration and Down-Regulation in Prostate Cancer
Our laboratory has previously identified soluble guanylyl cyclase α1 (sGCα1) as a novel androgen-regulated gene essential for prostate cancer cell proliferation. sGCα1 expression is highly elevated in prostate tumors, contrasting with the low expression of sGCβ1, with which sGCα1 dimerizes to mediat...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Endocrine Society
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275164/ https://ncbi.nlm.nih.gov/pubmed/22174378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0394 |
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