Soluble Guanylyl Cyclase α1 and p53 Cytoplasmic Sequestration and Down-Regulation in Prostate Cancer

Our laboratory has previously identified soluble guanylyl cyclase α1 (sGCα1) as a novel androgen-regulated gene essential for prostate cancer cell proliferation. sGCα1 expression is highly elevated in prostate tumors, contrasting with the low expression of sGCβ1, with which sGCα1 dimerizes to mediat...

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Detalhes bibliográficos
Main Authors: Cai, Changmeng, Hsieh, Chen-Lin, Gao, Shuai, Kannan, Archana, Bhansali, Meenakshi, Govardhan, Kumara, Dutta, Ranendra, Shemshedini, Lirim
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275164/
https://ncbi.nlm.nih.gov/pubmed/22174378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0394
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