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Using DNA methylation profiling to evaluate biological age and longevity interventions
DNA methylation levels of certain CpG sites are thought to reflect the pace of human aging. Here, we developed a robust predictor of mouse biological age based on 90 CpG sites derived from partial blood DNA methylation profiles. The resulting clock correctly determines the age of mouse cohorts, dete...
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| Publicado no: | Cell Metab |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5578459/ https://ncbi.nlm.nih.gov/pubmed/28380383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.03.016 |
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