Using DNA methylation profiling to evaluate biological age and longevity interventions

DNA methylation levels of certain CpG sites are thought to reflect the pace of human aging. Here, we developed a robust predictor of mouse biological age based on 90 CpG sites derived from partial blood DNA methylation profiles. The resulting clock correctly determines the age of mouse cohorts, dete...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Metab
Egile Nagusiak: Petkovich, Daniel A., Podolskiy, Dmitriy I., Lobanov, Alexei V., Lee, Sang-Goo, Miller, Richard A., Gladyshev, Vadim N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578459/
https://ncbi.nlm.nih.gov/pubmed/28380383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.03.016
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