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Specificity of mutations induced in transfected DNA by mammalian cells.

DNA transfected into mammalian cells is subject to the high mutation frequency of approximately 1% per gene. We present data bearing on the derivation of the two main classes of mutations detected, base substitutions and deletions. The DNA sequence change is reported for nearly 100 independent base...

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Detalhes bibliográficos
Main Authors: Miller, J H, Lebkowski, J S, Greisen, K S, Calos, M P
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC557826/
https://ncbi.nlm.nih.gov/pubmed/6098464
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