Transfected DNA is mutated in monkey, mouse, and human cells.

Papovavirus-based shuttle vectors containing the bacterial lacI gene were used to show that a mutation frequency in the range of 1% occurs in lacI when such vectors are transfected into COS7 and CV-1 simian cells, NIH 3T3, 3T6, L, and C127 mouse cells, and human 293 and HeLa cells. This frequency is...

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Библиографические подробности
Главные авторы: Lebkowski, J S, DuBridge, R B, Antell, E A, Greisen, K S, Calos, M P
Формат: Artigo
Язык:Inglês
Опубликовано: 1984
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC369011/
https://ncbi.nlm.nih.gov/pubmed/6095032
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