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High-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genome.

To examine the mechanisms of recombination governing the illegitimate integration of transfected DNA into a mammalian genome, we developed a cell system that selects for integration events in defined genomic regions. Cell lines with chromosomal copies of the 3' portion of the adenine phosphoribosylt...

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Udgivet i:Mol Cell Biol
Principais autores: Merrihew, R V, Marburger, K, Pennington, S L, Roth, D B, Wilson, J H
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230973/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.1.10
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