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Do Multiwell Plate High Throughput Assays Measure Loss of Cell Viability Following Exposure to Genotoxic Agents?

Cell-based assays in multiwell plates are widely used for radiosensitivity and chemosensitivity assessment with different mammalian cell types. Despite their relative ease of performance, such assays lack specificity as they do not distinguish between the cytostatic (reversible/sustained growth arre...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Mirzayans, Razmik, Andrais, Bonnie, Murray, David
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578069/
https://ncbi.nlm.nih.gov/pubmed/28767065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081679
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