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Do Multiwell Plate High Throughput Assays Measure Loss of Cell Viability Following Exposure to Genotoxic Agents?

Cell-based assays in multiwell plates are widely used for radiosensitivity and chemosensitivity assessment with different mammalian cell types. Despite their relative ease of performance, such assays lack specificity as they do not distinguish between the cytostatic (reversible/sustained growth arre...

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Pubblicato in:Int J Mol Sci
Autori principali: Mirzayans, Razmik, Andrais, Bonnie, Murray, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578069/
https://ncbi.nlm.nih.gov/pubmed/28767065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081679
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