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Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment

Tumors and tumor-derived cell lines contain polyploid giant cells with significantly elevated genomic content, often with multiple nuclei. The frequency of giant cells can increase markedly following anticancer treatment. Although giant cells enter a dormant phase and therefore do not form macroscop...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Mirzayans, Razmik, Andrais, Bonnie, Murray, David
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923373/
https://ncbi.nlm.nih.gov/pubmed/29662021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10040118
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