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Mutations of Pre-mRNA Splicing Regulatory Elements: Are Predictions Moving Forward to Clinical Diagnostics?

For more than three decades, researchers have known that consensus splice sites alone are not sufficient regulatory elements to provide complex splicing regulation. Other regulators, so-called splicing regulatory elements (SREs) are needed. Most importantly, their sequence variants often underlie th...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Grodecká, Lucie, Buratti, Emanuele, Freiberger, Tomáš
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578058/
https://ncbi.nlm.nih.gov/pubmed/28758972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18081668
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