Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation

BACKGROUND: Thiazolidinediones (TZDs), peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists, exhibit anti-inflammatory and antioxidant properties and inhibit endothelial inflammation and dysfunction, which is anti-atherogenic. However, fluid retention, which may lead to congestive heart fa...

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Vydáno v:BMC Pharmacol Toxicol
Hlavní autoři: Ku, Yun Hyi, Cho, Bong-Jun, Kim, Min Joo, Lim, Soo, Park, Young Joo, Jang, Hak C., Choi, Sung Hee
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577739/
https://ncbi.nlm.nih.gov/pubmed/28854981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0169-y
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