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Rosiglitazone increases endothelial cell migration and vascular permeability through Akt phosphorylation
BACKGROUND: Thiazolidinediones (TZDs), peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists, exhibit anti-inflammatory and antioxidant properties and inhibit endothelial inflammation and dysfunction, which is anti-atherogenic. However, fluid retention, which may lead to congestive heart fa...
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| Publicado no: | BMC Pharmacol Toxicol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577739/ https://ncbi.nlm.nih.gov/pubmed/28854981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0169-y |
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