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HPLC Purification of Chemically Modified RNA Aptamers
2′-Fluoro modified RNAs are useful as potential therapeutics and as special substrates for studying RNA function. 2′-Fluoro modified RNAs generally need to be purified after they are prepared either enzymatically or by solid-phase synthesis. Here we introduce a protocol by which 2′-fluoro modified R...
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| Publié dans: | Anal Biochem |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577503/ https://ncbi.nlm.nih.gov/pubmed/24373999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.12.022 |
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