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Developing RNA aptamers for potential treatment of neurological diseases

AMPA receptor antagonists are drug candidates for potential treatment of a number of CNS diseases that involve excessive receptor activation. To date, small-molecule compounds are the dominating drug candidates in the field. However, lower potency, cross activity and poor water solubility are genera...

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Detalhes bibliográficos
Publicado no:Future Med Chem
Main Authors: Huang, Zhen, Niu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Newlands Press Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661927/
https://ncbi.nlm.nih.gov/pubmed/30912676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2018-0364
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