Misidentified Human Gene Functions with Mouse Models: The Case of the Retinoblastoma Gene Family in Senescence()()()

Although mice models rank among the most widely used tools for understanding human genetics, biology, and diseases, differences between orthologous genes among species as close as mammals are possible, particularly in orthologous gene pairs in which one or more paralogous (i.e., duplicated) genes ap...

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Détails bibliographiques
Publié dans:Neoplasia
Auteurs principaux: Alessio, Nicola, Capasso, Stefania, Ferone, Angela, Di Bernardo, Giovanni, Cipollaro, Marilena, Casale, Fiorina, Peluso, Gianfranco, Giordano, Antonio, Galderisi, Umberto
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press 2017
Sujets:
Original article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577395/
https://ncbi.nlm.nih.gov/pubmed/28865301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.06.005
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