Mesenchymal stromal cells having inactivated RB1 survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy

Following radiotherapy, bone sarcomas account for a significant percentage of recurring tumors. This risk is further increased in patients with hereditary retinoblastoma that undergo radiotherapy. We analyzed the effect of low and medium dose radiation on mesenchymal stromal cells (MSCs) with inacti...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Alessio, Nicola, Capasso, Stefania, Di Bernardo, Giovanni, Cappabianca, Salvatore, Casale, Fiorina, Calarco, Anna, Cipollaro, Marilena, Peluso, Gianfranco, Galderisi, Umberto
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323029/
https://ncbi.nlm.nih.gov/pubmed/27124644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1175798
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