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The Polybasic Region of the Polysialyltransferase ST8Sia-IV Binds Directly to the Neural Cell Adhesion Molecule, NCAM

Polysialic acid (polySia) is a unique post-translational modification found on a small set of mammalian glycoproteins. Composed of long chains of α2,8-linked sialic acid, this large, negatively charged polymer attenuates protein and cell adhesion and modulates signaling mediated by its carriers and...

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Publicat a:Biochemistry
Autors principals: Bhide, Gaurang P., Prehna, Gerd, Ramirez, Benjamin E., Colley, Karen J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577389/
https://ncbi.nlm.nih.gov/pubmed/28233978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01221
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