Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells

BACKGROUND: Polysialic acid (polySia) is a carbohydrate modification of the neural cell adhesion molecule (NCAM), which is implicated in neural differentiation and plays an important role in tumor development and metastasis. Polysialylation of NCAM is mediated by two Golgi-resident polysialyltransfe...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Biotechnol
Main Authors: Somplatzki, Stefan, Mühlenhoff, Martina, Kröger, Andrea, Gerardy-Schahn, Rita, Böldicke, Thomas
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429572/
https://ncbi.nlm.nih.gov/pubmed/28499450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-017-0360-7
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