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Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells

BACKGROUND: Polysialic acid (polySia) is a carbohydrate modification of the neural cell adhesion molecule (NCAM), which is implicated in neural differentiation and plays an important role in tumor development and metastasis. Polysialylation of NCAM is mediated by two Golgi-resident polysialyltransfe...

詳細記述

保存先:
書誌詳細
出版年:BMC Biotechnol
主要な著者: Somplatzki, Stefan, Mühlenhoff, Martina, Kröger, Andrea, Gerardy-Schahn, Rita, Böldicke, Thomas
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429572/
https://ncbi.nlm.nih.gov/pubmed/28499450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-017-0360-7
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