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Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells

BACKGROUND: Polysialic acid (polySia) is a carbohydrate modification of the neural cell adhesion molecule (NCAM), which is implicated in neural differentiation and plays an important role in tumor development and metastasis. Polysialylation of NCAM is mediated by two Golgi-resident polysialyltransfe...

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Vydáno v:BMC Biotechnol
Hlavní autoři: Somplatzki, Stefan, Mühlenhoff, Martina, Kröger, Andrea, Gerardy-Schahn, Rita, Böldicke, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429572/
https://ncbi.nlm.nih.gov/pubmed/28499450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-017-0360-7
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