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PPARα-dependent Insig2a overexpression inhibits SREBP-1c processing during fasting
Peroxisome-proliferator-activated receptor alpha (PPARα) and sterol regulatory element-binding protein (SREBP) play a role in regulating cellular fatty acid and cholesterol homeostasis via fatty acid oxidation and lipogenesis. The control of SREBP processing is regulated by the insulin induced gene...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577246/ https://ncbi.nlm.nih.gov/pubmed/28855656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10523-7 |
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