PPARα-dependent Insig2a overexpression inhibits SREBP-1c processing during fasting

Peroxisome-proliferator-activated receptor alpha (PPARα) and sterol regulatory element-binding protein (SREBP) play a role in regulating cellular fatty acid and cholesterol homeostasis via fatty acid oxidation and lipogenesis. The control of SREBP processing is regulated by the insulin induced gene...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lee, Jae-Ho, Kang, Hye Suk, Park, Hyeon Young, Moon, Young-Ah, Kang, Yu Na, Oh, Byung-Chul, Song, Dae-Kyu, Bae, Jae-Hoon, Im, Seung-Soon
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577246/
https://ncbi.nlm.nih.gov/pubmed/28855656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10523-7
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