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Deletion of the IgH enhancer does not reduce immunoglobulin heavy chain production of a hybridoma IgD class switch variant.

Immunoglobulin (Ig) gene promotors are active only in cells of the B-lymphocyte lineage. Transfection experiments have shown that this is due in part to tissue specific 'activating' DNA sequences, so called enhancers. It is not entirely clear whether these sequences are necessary for initi...

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Bibliografske podrobnosti
Main Authors: Klein, S, Sablitzky, F, Radbruch, A
Format: Artigo
Jezik:Inglês
Izdano: 1984
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC557714/
https://ncbi.nlm.nih.gov/pubmed/6096124
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