Resolution Agonist 15-epi-Lipoxin A(4) Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing

Following myocardial infarction (MI), overactive inflammation remodels the left ventricle (LV) leading to heart failure coinciding with reduced levels of 15-epi-Lipoxin A(4) (15-epi LXA(4)). However, the role of 15-epi LXA(4) in post-MI acute inflammatory response and resolving phase is unclear. We...

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Udgivet i:Sci Rep
Main Authors: Kain, Vasundhara, Liu, Fei, Kozlovskaya, Veronika, Ingle, Kevin. A., Bolisetty, Subhashini, Agarwal, Anupam, Khedkar, Santosh, Prabhu, Sumanth D., Kharlampieva, Eugenia, Halade, Ganesh V.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577033/
https://ncbi.nlm.nih.gov/pubmed/28855632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10441-8
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