Thrombolysis by chemically modified coagulation factor Xa

BACKGROUND: Enzymatic thrombolysis carries the risk of hemorrhage and re-occlusion must be evaded by co-administration with an anticoagulant. Toward further improving these shortcomings, we report a novel dual-functioning molecule, Xai-K, which is both a non-enzymatic thrombolytic agent and an antic...

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Bibliografski detalji
Izdano u:J Thromb Haemost
Glavni autori: Pryzdial, E. L. G., Meixner, S. C., Talbot, K., Eltringham-Smith, L. J., Baylis, J. R., Lee, F. M. H., Kastrup, C. J., Sheffield, W. P.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576980/
https://ncbi.nlm.nih.gov/pubmed/27359348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13402
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