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Interaction of coagulation factor Xa with human platelets.

When human 125I-labeled Factor Xa is incubated with washed platelets, prothrombin, and Ca2+, a small amount of thrombin is formed which causes the platelet release reaction after a period of time that decreases as the Xa concentration is increased from 0.9 to 19 ng/ml. After a further lag period, th...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Miletich, J P, Jackson, C M, Majerus, P W
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1977
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431832/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/333455/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.9.4033
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