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The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes
Altered Ca(2+) handling is often present in diseased hearts undergoing structural remodeling and functional deterioration. However, whether Ca(2+) directly regulates sarcomere structure has remained elusive. Using a zebrafish ncx1 mutant, we explored the impacts of impaired Ca(2+) homeostasis on myo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | eLife |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
eLife Sciences Publications, Ltd
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5576919/ https://ncbi.nlm.nih.gov/pubmed/28826496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27955 |
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