Activation of AMPK inhibits cardiomyocyte hypertrophy by modulating of the FOXO1/MuRF1 signaling pathway in vitro

AIM: To examine the inhibitory effects of adenosine monophosphate-activated protein kinase (AMPK) activation on cardiac hypertrophy in vitro and to investigate the underlying molecular mechanisms. METHODS: Cultured neonatal rat cardiomyocytes were treated with the specific AMPK activator 5-aminoimid...

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Bibliografske podrobnosti
Main Authors: Chen, Bao-lin, Ma, Yue-dong, Meng, Rong-sen, Xiong, Zhao-jun, Wang, Hai-ning, Zeng, Jun-yi, Liu, Chen, Dong, Yu-gang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007721/
https://ncbi.nlm.nih.gov/pubmed/20581852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.73
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