Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain

Neuronal inhibition can occur via synaptic mechanisms or through tonic activation of extrasynaptic receptors. In spinal cord, glycine mediates synaptic inhibition through the activation of heteromeric glycine receptors (GlyRs) composed primarily of α1 and β subunits. Inhibitory GlyRs are also found...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: McCracken, Lindsay M., Lowes, Daniel C., Salling, Michael C., Carreau-Vollmer, Cyndel, Odean, Naomi N., Blednov, Yuri A., Betz, Heinrich, Harris, R. Adron, Harrison, Neil L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576794/
https://ncbi.nlm.nih.gov/pubmed/28784756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703839114
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