Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain

Neuronal inhibition can occur via synaptic mechanisms or through tonic activation of extrasynaptic receptors. In spinal cord, glycine mediates synaptic inhibition through the activation of heteromeric glycine receptors (GlyRs) composed primarily of α1 and β subunits. Inhibitory GlyRs are also found...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: McCracken, Lindsay M., Lowes, Daniel C., Salling, Michael C., Carreau-Vollmer, Cyndel, Odean, Naomi N., Blednov, Yuri A., Betz, Heinrich, Harris, R. Adron, Harrison, Neil L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576794/
https://ncbi.nlm.nih.gov/pubmed/28784756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703839114
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