Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain

Neuronal inhibition can occur via synaptic mechanisms or through tonic activation of extrasynaptic receptors. In spinal cord, glycine mediates synaptic inhibition through the activation of heteromeric glycine receptors (GlyRs) composed primarily of α1 and β subunits. Inhibitory GlyRs are also found...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: McCracken, Lindsay M., Lowes, Daniel C., Salling, Michael C., Carreau-Vollmer, Cyndel, Odean, Naomi N., Blednov, Yuri A., Betz, Heinrich, Harris, R. Adron, Harrison, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576794/
https://ncbi.nlm.nih.gov/pubmed/28784756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703839114
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