Acute Treatment with Doxorubicin Affects Glutamate Neurotransmission in the Mouse Frontal Cortex and Hippocampus

Doxorubicin (DOX) is a potent chemotherapeutic agent known to cause acute and long-term cognitive impairments in cancer patients. Cognitive function is presumed to be primarily mediated by neuronal circuitry in the frontal cortex (FC) and hippocampus, where glutamate is the primary excitatory neurot...

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Bibliografiske detaljer
Udgivet i:Brain Res
Main Authors: Thomas, Theresa Currier, Beitchman, Joshua A., Pomerleau, Francois, Noel, Teresa, Jungsuwadee, Paiboon, Butterfield, D. Allan, Clair, Daret K., Vore, Mary, Gerhardt, Greg A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576558/
https://ncbi.nlm.nih.gov/pubmed/28705715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2017.07.003
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