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A prebiotically plausible synthesis of pyrimidine β-ribonucleosides and their phosphate derivatives involving photoanomerization

Previous research into the prebiotic synthesis of the pyrimidine nucleotides has revealed a potential intermediate with remarkable properties – ribose aminooxazoline crystallises spontaneously from reaction mixtures, and with an enhanced enantiomeric excess if initially enantioenriched. This automat...

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Pubblicato in:Nat Chem
Autori principali: Xu, Jianfeng, Tsanakopoulou, Maria, Magnani, Christopher J., Szabla, Rafał, Šponer, Judit E., Šponer, Jiří, Góra, Robert W., Sutherland, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576532/
https://ncbi.nlm.nih.gov/pubmed/28338689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2664
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