Chromatin and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a regulator of primitive hematopoiesis

We analyzed chromatin dynamics and transcriptional activity of human embryonic stem cell (hESC)-derived cardiac progenitor cells (CPCs) and KDR(+)/CD34(+) endothelial cells generated from different mesodermal origins. Using an unbiased algorithm to hierarchically rank genes modulated at the level of...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Palpant, Nathan J., Wang, Yuliang, Hadland, Brandon, Zaunbrecher, Rebecca J., Redd, Meredith, Jones, Daniel, Pabon, Lil, Jain, Rajan, Epstein, Jonathan, Ruzzo, Walter L., Zheng, Ying, Bernstein, Irwin, Margolin, Adam, Murry, Charles E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576510/
https://ncbi.nlm.nih.gov/pubmed/28813672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.07.067
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