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Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes
During vertebrate development, mesodermal fate choices are regulated by interactions between morphogens such as activin/nodal, BMPs and Wnt/β-catenin that define anterior-posterior patterning and specify downstream derivatives including cardiomyocyte, endothelial and hematopoietic cells. We used hum...
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| Publicado no: | Development |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4582173/ https://ncbi.nlm.nih.gov/pubmed/26153229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117010 |
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