Circular oligomerization is an intrinsic property of synaptotagmin

Previously, we showed that synaptotagmin1 (Syt1) forms Ca(2+)-sensitive ring-like oligomers on membranes containing acidic lipids and proposed a potential role in regulating neurotransmitter release (Zanetti et al., 2016). Here, we report that Syt1 assembles into similar ring-like oligomers in solut...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Wang, Jing, Li, Feng, Bello, Oscar D, Sindelar, Charles Vaughn, Pincet, Frédéric, Krishnakumar, Shyam S, Rothman, James E
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576491/
https://ncbi.nlm.nih.gov/pubmed/28850328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27441
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